Nucleic Acid Design & Analysis.

From DNA, RNA and mRNA to tRNAs, guide RNAs, aptamers, duplexes and specialised nucleic acid complexes, Vici.bio helps teams predict structure, model co-folding, optimise sequences and analyse deeper nucleic-acid interactions.

DNA and RNA structure prediction with co-folding
Structure Prediction

Fold DNA, RNA & co-fold complex systems.

Predict nucleic acid structures, model duplexes, hairpins and larger assemblies, and support harder cases like protein-DNA, protein-RNA, ligand-bound RNA and broader co-folding workflows.

RNA folding, tRNA and specialised RNA systems
RNA Systems

Work across mRNA, tRNA, aptamers & guide RNAs.

Analyse mRNA, tRNAs, guide RNAs, aptamers, ribozymes and other structured RNA systems where local motifs, loops, pairing patterns and binding context all matter.

Protein nucleic acid binding and interface analysis
Binding & Interfaces

Model nucleic acid binding in full context.

Explore protein-DNA and protein-RNA interfaces, inspect binding contacts, compare structural states and support workflows where recognition, specificity and nucleic-acid conformation must be analysed together.

Nucleic acid sequence editing and design
Sequence Editor & Optimisation

Edit bases, motifs & full nucleic variants.

Use the editor to mutate bases, redesign motifs, optimise oligos, adjust loops, tune guide sequences and move faster from sequence editing to structure-aware analysis.

Ligands, metals and modified nucleotides in nucleic acid systems
Ligands, Ions & Modified Bases

Handle the chemical context around nucleic acids.

Support metal ions, small-molecule binders, modified nucleotides, base analogues and other chemically enriched cases where folding, recognition and stability depend on more than sequence alone.

Specialised DNA and RNA architectures
Specialised Architectures

Work across duplexes, loops & rare nucleic forms.

Go beyond the obvious with stem loops, structured motifs, duplex variants, specialised RNA folds and harder nucleic-acid architectures that still need strong modelling, optimisation and interaction support.

Nucleic acid dynamics and conformational changes
Dynamics & Ensembles

Simulate flexibility, motion & structural change.

Run molecular dynamics, inspect conformational changes, compare flexible states and support nucleic-acid systems that cannot be understood from a single static structure, especially in larger or more dynamic assemblies.

Explore nucleic acid models, editor tools & workflows on Vici.bio.

From folding and co-folding to sequence editing, interaction analysis, modified-base modelling and molecular dynamics, build nucleic-acid workflows designed for modern computational biology.